Press Release
Rosie O’Donnell Shares Weight Loss Success with Mounjaro
In a heartfelt update shared on social media, Rosie O’Donnell has revealed significant progress in her weight loss journey, attributing her success to the diabetes medication Mounjaro (tirzepatide). Announcing the news in May 2025, O’Donnell noted that along with managing her diabetes, she has also shed pounds—somewhat unexpectedly—as a side effect of the medication.
Mounjaro is classified similarly to Ozempic and Wegovy, utilizing GLP-1 to assist in both diabetes treatment and weight loss. While some users have reported side effects like nausea and diarrhea, O’Donnell expressed her astonishment at her new size, stating, “I find it completely shocking.”
Celebrities such as Whoopi Goldberg and Amy Schumer have also publicly acknowledged their weight loss experiences with Mounjaro. Goldberg, during a recent appearance on The Kelly Clarkson Show, revealed that she lost the equivalent of "almost two people," appreciating the support the medication provided amid life’s other stresses. Similarly, Schumer shared her favorable experience after previously trying Wegovy.
Other notable names like Meghan Trainor and Scott Disick have entered the conversation, with Trainor and her husband both using Mounjaro after welcoming their son. Disick, in an episode of The Kardashians, unabashedly discussed his use of the medication while addressing online speculation regarding his weight loss.
As more celebrities openly discuss their journeys with Mounjaro, the conversation around the medication and its implications for weight management continues to evolve. O’Donnell’s story, marked by determination and transformation, resonates as an empowering narrative for those facing similar challenges.
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